Bacteriophages are among the most common and diverse entities in the biosphere. Many studies have shown that the application of phages in bacterial therapy or biocontrol is possible, but the practical results have not been successful due to the lack of full coverage of target bacteria and the rapid emergence of bacterial mutations leading to complete resistance against phage infection. Furthermore, the development of phage-neutralizing antibodies is another possible problem which may hamper phage effectiveness in lysing targeted bacteria in vivo.
ABR has been able to overcome these hurdles, and is able to help companies and research institutes by providing them with great solutions to produce the non-genetic phage programming technology, which is used to produce smart lytic phage with a very destructive killing index on multidrug resistant bacteria.
Dr. Sabah Jassim spent most of his professional career as a Medical Microbiologist studying and experimenting with bacteriophages. The culmination of his life’s work is reflected in his book “Bacteriophages: Practical Applications for Nature’s Biocontrol:
https://www.springer.com/us/book/9783319540504#otherversion=9783319540511
Chapter 1: Enhanced Bacteriophages
Chapter 2: Bacteriophage and Antimicrobial Resistance
Chapter 3: Bacteriophage Biocontrol in Poultry
Chapter 4: Control, Prevention and Rapid Detection of Methicillin-Resistant Staphylococcus aureus
Chapter 5: Reducing Greenhouse Gas Emissions from Livestock Farms
Chapter 6: Bacteriophage Biocontrol: Deployment in Aquatic Ecosystems
Chapter 7: Bacteriophage Biodefense
Chapter 8: Discussion and General Conclusions
More information regarding the non-genetic phage programming technology to produce smart lytic phage can be found at:
Jassim S. A. A. et al. 2017 “Bacteriophages: Practical Applications for Nature’s Biocontrol:
https://www.springer.com/us/book/9783319540504#otherversion=9783319540511
Chapter 1: Enhanced Bacteriophages
Jassim S. A. A. et al. 2014. Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’. World Journal of Microbiology and Biotechnology 30(8):2153-2170. http://link.springer.com/article/10.1007%2Fs11274-014-1655-7#.
ABR is able to assist with personnel training, facility construction consulting, and phage growth process optimization.